Definition
To continue functioning or working despite having depleted one's energy reserves; often implies being active or productive while being exhausted.
强努支撑（在精疲力竭的情况下继续工作）
After working for 12 hours straight, she felt like she was running on empty.
连续工作了12个小时后，她感觉自己已经筋疲力尽了。
He has been working overtime a lot lately; I am worried he is running on empty.
他最近经常加班；我担心他已经筋疲力尽了。
After finishing the marathon, I felt like I was running on empty.
跑完马拉松后，我觉得自己已经筋疲力尽了。
(US) To describe a person or an organization that has run out of new ideas or is no longer operating as effectively as before; implies a state of stagnation or lack of momentum.
后劲不继
Since the main founder left, the startup feels like it’s running on empty.
自从主要创始人离开后，这家初创公司感觉就像在空转。
After a few years of success, the team seems to be running on empty.
在几年的成功之后，团队似乎已经没有动力了。
Without new leadership and vision, the organization is running on empty.
没有新的领导和愿景，这个组织正在空转。