Definition
Used to express a firm determination to accomplish something, regardless of any difficulties or obstacles that may arise.
即使千辛万苦，也必须……
I will finish this report by the deadline, come hell or high water.
我一定会在截止日期前完成这份报告，无论遇到什么困难。
They are determined to make this project a success, come hell or high water.
他们决心让这个项目成功，无论遇到什么困难。
She vowed to get that degree, come hell or high water.
她发誓要拿到那个学位，无论遇到什么困难。