Definition
to dislike or be annoyed by something or someone; to find something or someone unacceptable.
对某事或某人感到厌恶或反感
I have a problem with people who talk loudly in the library.
我对在图书馆大声说话的人有意见。
My colleague has a problem with me always being late.
我的同事对我一直迟到有意见。
I don't have a problem with him; I think he's fine.
我对他没有意见；我觉得他很好。