Definition
an informal expression indicating a significant mistake or poor performance in executing a task
弄坏某事；搞砸；损毁
He really cocked up the presentation with several mistakes.
他真的把简报搞砸了，犯了几个错误。
If you don’t double-check, you might cock up the whole project.
如果你不仔细检查，可能会搞砸整个项目。
Her miscalculations cocked up the entire experiment.
她的计算错误搞砸了整个实验。