Definition
to secure all the doors and windows of a structure before departing
锁上所有的门窗
Before we leave, make sure to lock up all the doors and windows.
我们离开前，确保锁上所有的门窗。
He always locks up all the windows when he goes on vacation.
他去度假时总是会锁上所有的窗户。
She carefully locks up every entrance after closing the store in the evening.
她晚上关店后会仔细锁上每个入口。