Definition
to be in opposition to someone or something, or to have an adverse impact on them.
对抗…；违背…；不利于…
This policy runs against the best interests of the community.
这项政策违背了社区的最佳利益。
His proposed suggestions run against traditional beliefs.
他提出的建议与传统信仰相悖。
This approach runs against the growth of the business.
这种方法不利于业务的增长。