Definition
To be in a position of authority to make the important decisions that direct a situation or project.
医定行动方针
In this project, the manager is the one who calls the shots.
在这个项目中，经理是掌握决策权的人。
As the CEO of the company, she has the power to call the shots on the direction of its development.
作为公司的CEO，她有权决定公司的发展方向。
When it comes to the budget, the finance department is really the one that calls the shots.
在预算方面，财务部门才是真正掌握决策权的。