Definition
To establish and begin operating one's own business.
开始经营自己的事业或公司。
After many years of experience in the industry, he decided to set up shop on his own.
在行业中累积多年经验后，他决定自己创业。
They rented a storefront downtown, ready to set up shop.
他们在市中心租了一个店面，准备开业。
She quit her old job, determined to set up shop with her own design studio.
她辞去了旧工作，决心开设自己的设计工作室。