Definition
To exert oneself with extreme effort; to work, play, or fight with maximum intensity.
拼命工作（拼命做事）
We have to work our guts out to meet the deadline.
我们必须全力以赴，以赶上截止日期。
He played his guts out in practice to win the competition.
他在练习中全力以赴，以赢得比赛。
The team fought their guts out, but they still lost.
团队拼尽全力，但还是输了。