Definition
to exhaust yourself to the point of becoming unwell
累垮身体
If you keep working overtime all week, you will eventually run yourself down.
如果你整个星期都加班，你最终会把自己累垮。
He is always busy with work and never takes a break; at this rate, he will run himself down.
他总是忙于工作，从不休息；照这样下去，他会把自己累垮。
Exercise is good, but overdoing it can run yourself down.
运动是好的，但过度运动会让自己累垮。