Definition
an impolite expression used to describe causing damage, harm, distress, or failing at a task severely
弄壞；破壞；使困擾；搞砸
His carelessness really fucked up the entire project.
他的粗心大意真的搞砸了整個專案。
If we don't double-check, we might fuck up the key data in the report and ruin the presentation.
如果我們不仔細檢查，可能會搞砸報告中的關鍵數據，毀了整個簡報。
She didn’t know how to use the new software, and in the end, she fucked up the system.
她不知道如何使用新軟體，最後把系統搞壞了。